This site is intended for healthcare professionals

Sign in
Go to /sign-in page

You can view 5 more pages before signing in

Switching antidepressant (SSRIs to mirtazapine) in adults

Authoring team

SSRIs to mirtazapine

Cross-taper

  • cross-tapering can generally be undertaken cautiously over 2 to 4 weeks, the speed is determined by individual tolerability

Additional caution when switching from fluoxetine

  • fluoxetine may still cause medicine interactions 5 or 6 weeks after stopping, as fluoxetine and its active metabolite have a long half-life

Additional caution when switching from fluvoxamine

  • start mirtazapine at a dose of 15mg daily.
    • this caution is required because fluvoxamine is a potent inhibitor of the liver enzyme CYP1A2 which is involved in the metabolism of mirtazapine
      • is therefore a risk of raised mirtazapine levels in the body when they are administered together

Reference:

Related pages

Create an account to add page annotations

Create a free account

Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.