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Gastrointestinal manifestations

Authoring team

GI disturbances are common in SLE patients and may be due to primary gastrointestinal disorders, complications of therapy or SLE itself (1).

GI manifestations in SLE include:

  • oral ulceration - is a common feature
  • nausea, vomiting, or anorexia occur in about 20% of cases
  • abdominal pain - may be due to active lupus, including peritonitis, pancreatitis, mesenteric vasculitis, and bowel infarction
  • jaundice - due to autoimmune hepatitis (1)
  • ascites is rare but often massive
  • hepatomegaly occurs in about 30% of cases
  • splenomegaly occurs in about 20% of cases and is unusually associated with haemolytic anaemia

Reference:

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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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