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Pioglitazone and psoriasis

Authoring team

  • there is some evidence for the role of inflammation and insulin resistance in the pathophysiology of plaque psoriasis. Thiazolidinediones are antidiabetic drugs that act by improving insulin sensitivity and also possess anti-inflammatory effects
  • a systematic review and meta-analysis was performed to assess the efficacy of thiazolidinediones on psoriasis severity
  • the study authors concluded that '..Pioglitazone appears to have efficacy for the treatment of psoriasis...'

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