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Antidepressant treatment and non-steroidal anti-inflammatory drugs (NSAIDs)

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Non-steroidal anti-inflammatory drugs (NSAIDs)

NICE suggest that clinicians should:

  • not normally offer SSRIs - but if no suitable alternatives can be anti-inflammatory drugs identified, offer gastroprotective medicines (for example, proton pump (NSAIDs) inhibitors) together with the SSRI
  • consider mianserin, mirtazapine, moclobemide, reboxetine or trazodone

Reference:

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