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Prognostic indicators

Authoring team

Good

Bad

Presenting white cell (important)

less than10 x 10^9 /litre

more than 50 x 10^9 /litre

Age

2-10 years

less than 2 years more than 15 years

Sex

Female

Male

Clinical

remission within 4 weeks

CNS leukaemia

Organomegaly

absent

hepatosplenomegaly

CNS involvement

absent

present

Morphology

L1

L3, better than L2

Phenotype

cALL

B-ALL

Chromosomes

hyperploidy - more than 50 chromosomes, translocations

hypodiploidy less than 46 chromosomes


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