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Major histocompatibility antigen class I

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

MHC class I has alleles at the A, B, C loci on chromosome 6.

Features are as follows:

  • two chain structure; an alpha and beta chain
  • expressed on all nucleated cells
  • mainly concerned with the recognition of viral antigens by cytotoxic T cells

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