CREST syndrome
CREST - is a localised form of systemic sclerosis associated with a better prognosis. It comprises:
- Calcinosis - palpable nodules in the hands due to calcific deposits in the subcutaneous tissue
- Raynaud's phenomenon - ischaemia resulting in atrophy of the finger pulps
- oEsophageal dysmotility - if absent, then CRST syndrome
- Sclerodactyly - tightening of the skin of the fingers resulting in tapering
- Telangiectasia - multiple, large and on the fingers
Tethering of the skin proximal to the wrists, on the legs or trunk suggests systemic sclerosis.
The features of the different forms of systemic sclerosis have been described (1):
Reference:
- 1) Arthritis Research Campaign (2010). Topical Reviews - Systemic sclerosis and related disorders
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